Supercritical Fluid Extraction (SFE) Systems

Waters' Supercritical Fluid Extraction (SFE) Systems extract chemical compounds using supercritical carbon dioxide instead of an organic..

The supercritical fluid state occurs when a fluid is above its critical temperature (Tc) and critical pressure (Pc), when it is between the typical gas and liquid state. Manipulating the temperature and pressure of the fluid can solubilize the material of interest and selectively extract it. The sample is placed in an extraction vessel and pressurized with CO2 to dissolve the sample. Transferred to a fraction collector, the contents are depressurized and the CO2 loses its solvating power causing the desired material to precipitate. The condensed CO2 can be recycled.

SFE applications in the food, pharmaceutical, and fine chemical industries:

  • Decaffeinating of coffee and tea
  • Extraction of essential oils (vegetable and fish oils)
  • Extraction of flavors from natural resources (nutraceuticals)
  • Extraction of ingredients from spices and red peppers
  • Extraction of fat from food products
  • Fractionation of polymeric materials
  • Extraction from natural products
  • Photo–resist cleaning
  • Precision part cleaning

SFE Bio-Botanical Extraction System
The Waters Bio-Botanical Extraction System is a multi-vessel supercritical fluid extraction system ideally suited to rapidly and automatically extract large quantities of desired components from a multitude of botanical matrices.


MV-10 ASFE System
The MV-10 ASFE System features accelerated, multi-vessel sample extraction, using environmentally friendly CO2 as the mobile phase, for a greener and more selective alternative to normal phase extractions.


Prep SFE Systems
Waters' Prep Supercritical Fluid Extraction (SFE) systems and extraction equipment extract chemical compounds using supercritical carbon dioxide instead of an organic solvent.

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